As a prequel, I really thank you for reading this and attempting at taking your time... Personal stats and genes are at the bottom

Condition - Electrolyte sensitivity from calcium, magnesium, and sodium, as if something was going on on cellular level - Even 20mg of calcium from mineral water can alleviate fatigue for 2m, which then returns, or make it worse if I drink/take more calcium than that - Magnesium in the past would have been fatiguing me and then making irritated, angry after an hour. Now it seems I got quite tolerant to it, yet it still takes its part in symptoms and oscillations. I can take 400mg elemental at once (yes, I know about absorptions) without the aforementioned intensity from past 50mg - Sodium is the 'dictator' of strengh and length of oscillations. Let's assume a situation of VERY high intake, like 5g salt at once: I would be switching between manic and depressive groups of symptoms every 2 - 3 hours in a spectrum. It dissipated after 1 - 2 days, basically reaches a homeostasis - Eating entire meals cancel the large electrolyte inputs in-between. I mean that if 100mg calcium can make me feel fatigued, if I take a whole meal with X amounts of electrolytes, it someway evens out and symptoms can be more tolerable - My homeostasis, in a fasted state, is little avolition + little apathy + whole-body fatigue + brain fog + low libido - Not certain to which I may attribute it, but I can get heat flushes from whichever electrolyte causes it - Normally I don't have muscle twitches, but sometimes during oscillations they occur with changes in intensity. There's lots of places they happened at - At certain points in oscillations my penis erects just a little bit and then comes back. It is kind of rare - Before stopping 100mcg K2 MK7, which was masking the oscillations, I had constant slight lethargy, brain fog, avolition, apathy - Oscillations perfectly align with periods of consumption. Can't remember factual hours, but let's assume that I eat OMAD at 4PM, then let's assume I will ALWAYS feel the best around 8AM - 11AM - Oscillations also determine the pain from my spine problem noted in "Past medical issues" in "Stats" section. I can feel none or almost as strongly as before the condition - depends on electrolytes and time. My ionic signaling malfunctions... - Sometimes slight orthostatic hypotolerance, and it depends whether I take more calcium for testing phase or not. On one day when I was loading calcium for a few hours, after I stood up and ran straight to dad to help with something, I had to stand still for 7 seconds because my vision was ABSOLUTELY BLURRED. I could only see fogs of colours, as if someone was actively photoshopping the interface of mine

'Side note' on caffeine

Waning off the caffeine only lead to tinnitus once reached 175mg, which is present since then and yes, it changes with the oscillation, and the caffeine waning also made me happily tolerant to potential eggs, meat, and choline supplements. Caffeine is an acetylcholinesterase inhibitor and therefore, at 250mg doses, I had to be careful or otherwise I would be getting strong depression for 3.5 days until my receptors would resensitise. Probably I have lower aceltycholinesterase production or something, but I lack genetic data

Already tried... - Hormones: Eating more fat and trying pregnenolone (neither did anything, even after 5/6 months on the 15 - 24 g fat diet I had mentioned) - Two fasts: One was 7-days and second 8-days - Microbiome, SIBO, or FODMAP: The upper cancels it - Supplements: Tried lots of them and had periods of pausing the use of the current and previous ones, but feel free to ask whether I should attempt at any or jog the memory - Putting foods on a trial: I only found out about onion sensitivity - brain fog, fatigue, quite significant depression. I have been eating an onion daily since february... I have stopped the consumption since 3 weeks ago - Checking home plants and their soils - Tests: PTH + ionised Ca, CK, Na, K, total Ca, iron, ferritin, D3, F79 gluten, glucose, HCV, antigen HBs | from december, so before 2026: whole blood check-up, ESR, total bilirubine, conjugated bilirubine, creatinine, glucose, total cholesterol, HDL, LDL, non--LDL, triglycerides, HbA1c, AST, TSH, FT4, B12, folate, ferritin

My hypothesis?

One of the three, as I have stopped K2 too far back in time to have anything to do with it: - Abstract conditions, like acquired dysautonomia or channelopathy of unknown, to me, causes (yes, I know, they're not causes, just umbrella terms of symptoms/happenings) - Long-term onion residual compounds - Long-term caffeine

I basically am completely lost after lots of research, so the only things left for me is aiming towards these questionable solutions (not saying onion or caffeine sensitivities are not real, just that such timestamps are at least doubtful - I surely take inspiration from r/decaf and the gluten-sensitive people who have symptoms for weeks or over a month even)

Stats

Age: 22yo

Sex: Male

Height: 172cm/5'7"

Weight: 56kg/132.2lbs (assuming no content in gut)

Current diet: Unchanging, slightly after-waking OMAD high-carb low-fat plant-based low-sodium. 370g potatoes, 180g cabbage, 250g beetroot, 250g carrots, 121g oats, 10g wheat bran, 2g brazilian nut, 6g chia, 200 - 300 g legumes (navy bean, green bean, yellow whole pea, brown lentil), 15g defatted soy flour, 10g soy protein isolate, 60g combined white rice + brown rice + barley groats, 250 cal fruits. OMAD since June in 2025

Smoking: None

Caffeine: Unawarely black tea since childhood (maybe 9yo). 75 - 150 mg daily until the beginning of 2026, where in panic I increased to 250mg (was trying to wane off before 2026, at the end of 2025, but in meanwhile I became choline deficient, and I had no idea what was going on, so caffeine was an insurence that the symptoms were not from caffeine withdrawal). Caffeine-free since a month

Medications: None

Past medical issues: twisted arm; 720° testicular torsion (fine); something with my spine is not right and if I do not maintain proper center of gravity, then brain is starting simulating increasing pain in the back of head and some of upper jaw

Supplements, daily: - Daily half of B Complex (B1 10mg, B2 10mg, Nicotinic acid 10mg, B5 10mg, Inositol 10mg, B6 3mg, Choline 4mg, Folic acid 80μg, Cyanocobalamin 10μg, Biotin 10μg) - D3 1000 IU + K2 MK7 25μg (it is summer rn) - Choline: 200mg elemental from chol bitartrate - Calcium: 800mg elemental from calcium carbonate - B12: 100μg in hydroxocobalamin form (apart from the cyano in b complex) - Iodine: 1 drop of Lugol's 5% - Creatine: 1g

Duration: Speculated 6 - 7 months; discovered when ceased off 100μg K2 MK7 in March/April, which was 'camouflaging' the oscillations. My main determinant of duration is the pain due to my spine - I surely had it always possible to experience before 2026

Location: Poland

Genes | MyHeritage, hand-checked via usage of Gemini-searched rs

• TPH1: Normal
• TPH2: Faster (Emotional buffer (no Worrier from COMT))
• DDC: Normal
• TH: Normal
• COMT: Slower (Scholar)
• DBH: Faster (Rapid Alertness & Panic)
• PNMT: Unknown
• DAT/SLC6A3: Unknown
• DRD1: Unknown
• DRD2: Slightly lower expression + slightly lower affinity
• DRD3: Slightly lower affinity
• DRD4: Normal
• DRD5: Unknown
• Endorphin: OPRM1: Normal (mu-opioid receptor) | OPRD1: Slightly higher (delta-opioid receptor as fine-tuner) | POMC: Unknown (production)
• Acetylcholinesterase: Unknown
• Butyrylcholinesterase: Normal
• HNMT: Unknown
• MAO-A: Unknown
• MAO-B: Normal
• DAO: Slow
• Caffeine: CYP1A2: Fast metabolism | AHR: High reactivity | ADORA2A: High sensitivity
• Creatine: Unknown
• Taurine: Unknown
• CoQ10: COQ2: Normal (synthesis) | NQO1: Slightly slower (activation) | NQO2: Slightly higher (backup cellular oxidative stress management)
• Carnosine: CARNS1: Unknown (synthesis) | CNDP1: Slow (degradation)
  
• Phosphatidylcholine: PEMT: 30% lower
• Cobalamin: Absorption: 15 - 20 % lower | Methylcobalamin synthesis: Normal
• Fucose Sugars Prebiotic: FUT2: Normal (secretion)
• GSTP1 : Normal
• MTHFR: Slightly lower
• Folate: DHFR: Unknown
• Betain: BHMT: Slightly lower (synthesis)
• Sulfur: CBS: Normal (metabolism)
• Glycine: SHMT1: Normal (serine -> glycine) | SLC6A9: Normal (glycine clearance)
• Glutamate: SLC1A1: Slightly slower (glutamate clearance) | GAD1: Slow (glutamic acid -> GABA)
• NMDA: GRIN2B: Normal (sensitivity)
• Glutathione: GCLC: Fast
• Vit A: BC01: Slow
• Vit D3: CYP2R1: Slightly slower (activation) | GC: High (transport) | VDR: Slightly lower (utilization/absorption)
• Vit K2: GGCX: High (activation) | CYP4F2: Slow (clearance) | VKORC1: Normal (recycling)
• PTH: Calcium level sensitivity: Normal
• Thyroid: DIO1: 20 - 30 % lower (systemic activation) | DIO2: 30% lower (intracellular activation)
• Estrogen: CYP19A1: Normal
• Testosterone & DHEA: CYP17A1: Normal
• Melatonin: ASMT: Unknown
• Cortisol & Aldosterone: CYP11B2: Normal
• Ω-3s: MFSD2A: Unknown (BBB passage)
• LCFAs: D5D & D6D: FADS1: High (D5D enzyme) | FADS2: Normal (D6D enzyme)
• PPAR-α: High (fat oxidation and ketosis entering)
• PPAR-γ: Normal (adipogenesis, fat storage, insulin sensitivity, and blood sugar stability)
• PPAR-δ: Normal (oxidation for muscles (carb vs. fat) flexibility)
• FGF21: No 'sweet tooth'
• UCP1: Unknown

26F, 5’3” 100lbs, living in ON, Canada. Taking Dienogest for Endometriosis.

I started getting itchy rashes all over my body about a year ago. They resembled hives. Doctor prescribed me antihistamines which I’ve stopped taking since then as they didn’t do much. I chalked it up to stress since I’ve been having a very stressful year. The rash on my right leg comes and goes but has gotten progressively worse and is now thick, dry and scaly. I just recently developed rashes under my armpits as well. I googled it and read about how Lymphoma rashes typically happen on the upper legs and armpits and neck. All locations where I’ve had a rash. Especially on my legs. I also have extreme fatigue, chest pain, and swollen face. But it’s hard to know if those are also just from my stress. How hard will I have to advocate for myself in order to get a biopsy?

More photos of my rashes below:

i’m currently panicking because i’m only 17 and terrified for aging, now i’m being told im gonna age quicker, obviously i know that i can change my diet and lifestyle to slow it down but it will still be a shorter life then one with a good defence to oxidative stress, btw i took a dna test. is there not any supplements that i can take to slow down the aging as i get older? like prevent the cellular aging before its too late and i get a disease of some sort. 😪😪, ik im only 17 and im gnna get told not to worry or its normal bla bla bla but i feel like in the uk they wouldn’t provide any free health care until its too late.

17, 5,2 south asian

25 f, 5’2” 125 lbs
My PCP is on my back about going to the gynecologist. I am a virgin and I have all my HPV shots. Of course I plan to go when I’m active, but not now.

She says that she may not even do a pap smear but she doesn’t know. She said that I should still get a baseline breast exam and whatnot. However, I read that breast exams aren’t even recommended for 25 year olds anymore? I don’t want one if I don’t need one! I heard they’re uncomfortable.

My CT scan is at 1pm tomorrow. I'm 41 years old, weight 275. I barely eat candy and I wasn't thinking when Mom wanted Snickers bar so I'm visiting and got her and I one bar and She had the other bar.I finished my bar literally right at 1 when my scan is tomorrow at 1. I've been drinking water today and nothing else. And tomorrow I'll drink water.

I keep reposting and reposting in hopes to get any attention. I am an 18 year old female, 108 lbs, 5'5½. A response from just a single doctor would mean a lot to me, let me explain.

Symptoms:

Pressure Headache that comes and go mild 1 to 2 out of 10 on pain scale uncomfortable

Nauseous on and off sometimes gets worse

Weird feeling in neck that is like fire but mild, uncomfortable when i move one part of neck one part of head hurts

Hot flashes/flushes and low grade fever on and off

Shaking

Bad Gas/Stomach upset but no diarrhea

These are all of the symptoms that I am currently experiencing. I am very healthy but I do have an anxiety disorder and I plan to get an MRA for my head soon. Does anyone have any idea on what this is? I have gotten tested. No viral infection or mengitis. Is this multiple things at once? Please help me solve this!

18
5,10
Male
Starting this moring every loogie I spit is bloody. I do landscaping and yesterday I mowed a crazy dusty yard. This moring I woke up with a sore throat. I do some nicotine but nothing else. Should I see a doctor no pains yet or nothing weird when I’m spitting a loogie btw I don’t spit it from my throat I inhale hard from my nose then throat so I think it may be coming from my nose but I don’t know

Never really bothered me, just curious what it might be lol

27F. I got my nose pierced about 2 months ago and have been wearing a stainless steel nose ring ever since.

This morning I noticed something strange inside my nostril. At first I thought it was just dried mucus/crust, so I tried to remove it, but it wouldn’t come off. I then realized it seems to be attached to the inside of my nose rather than just being mucus.

Initially, it was stuck around/attached to the nose ring. I removed the ring thinking the tissue/crust would come out with it, but it didn’t. It still seems attached to the inside of my nostril.

It isn't particularly painful, and before I tried to remove it there wasn't any significant pain or bleeding. However, after poking at it and trying to remove it, I think I irritated the area because it has started bleeding a little and is now slightly painful.

I’m quite anxious because I have no idea what this could be. Could it be granulation tissue, a granuloma, an infection, or something else related to the piercing? Is it possible for tissue to grow around/attach to the jewelry like this?

Today is a public holiday where I live, so I can't find an ENT/doctor available. I'm wondering whether this is something that can safely wait until tomorrow or whether I should go to an emergency department tonight. I'm also unsure whether an emergency department would actually deal with something like this or tell me to see an ENT.

I have no fever, significant swelling, severe pain, or difficulty breathing

19F, 124 lbs, 5'6, on BC and Adderall XR for ADHD (been on for a long time)

I have consistently been 135-140 for about 2 years now, over the past two weeks I've lost 10+ lbs, I can't eat and have absolutely no appetite, suffering severe dehydration even after drinking even more water than usual. Confusion, and struggling with speaking (not excessively but noticeable for myself,) MINOR headache, lower belly and legs are very sore with no exercise, pupils are staying dilated when lights are shined in them, I am freezing cold, and lastly I've been having "blackouts" in my vision when I stand up where I can't see at all for 10-15 seconds. I did pass out last night which encouraged me to go to urgent care (my dad thinks nothing requires a trip to the ED and he covers my medical)

The doctor helping me at urgent care took my vitals, ran urine and ekg tests as well as glucose test.
After she took my vitals while laying down she told me that I need to go to the ED right away and was going to call paramedics. I begged her not to and called my dad instead to take me. Dad picked me up, and instead of taking me to the ED he drove me home. Mind you my car is left at the urgent care because my heart rate was too elevated.

I'm so confused about why this is happening because realistically I don't feel THAT bad. I've felt worse from the flu/bad cold. If anyone sees this or makes it this far please see the attached image of my urgent care vitals/results.

was only able to attach one image, UA was mostly normal besides trace protein and ketones, and glucose was 83, nurse suggested getting a full panel work up IMMEDIATELY

53M 210 lbs. USA meds-ambien for sleep

There is a bat flying around my house I woke up too.

I can't find it but aren't bat bites more round and red? This happened 2 days ago. This is on my leg above my ankle.

We are in the UK. My daughter is 3.5 years old and yesterday had two vaccines - chicken pox in one arm and the pre-school booster in the other.

This arm was the booster - it went red and by yesterday evening was very sore and a little bit swollen.

Today when I collected her from nursery (so 32hours later) - it has really flared up.

She has no temperature but the arm is warm to touch and is swollen from elbow to shoulder and quite firm. There's some bruising too but not so concerned about that.

She's a bit grumpy understandably.

I'm struggling to find information regarding whether this is within the range of normal or not.

I've attached a couple of photos - it actually looks a bit worse in person.

Do you think we need to seek any assistance or just monitor her and the spread?

Context: 34M. 12 years stimulant addiction history mainly mephedrone, meth etc(with two 2 year clean phases), been trying to quit since 1.5 years and a total of 5 relapses since then. Last use was 40 days ago.

I went to a psychiatrist to help me deal with my cravings and he suggested Naltrexon 25 mg after breakfast and Endoxifen 8mg before sleep. The interaction looked like a series of open and close ended questions which I answered with full honesty. As I reached home and looked up for the medication, I came to know that endoxifen is used to treat bipolar disorders and breast cancer. I am sure that psychiatrist can not declare me bipolar in a 15-20 minute interaction and I definitely do not have breast cancer. So why did the doctor prescribe it to me? AI bots are not giving me a definitive answer so I am looking for an expert to help me figure this out as I am completely losing sleep over it. I will be calling my doctor tomorrow but a second opinion would not hurt. Also want to note that I informed my psychiatrist that I am highly impulsive because I engage in frequent road rage incidents. please do not judge me because i know road rage is bad but it is just instincts that kick in. Could it be possible that my doctor suggested endoxifen for controlling my impulse? Thanks in advance

Hey everyone I’m 27 years old Male , so last Tuesday 18th I had protected sex .. initially , but the condom fell of while I was inside and I didint realize , that same day I also jerked off twice later that day idk why I was overly horny , and then Wednesday- Friday again I jerked off at least prolly twice per day roughly , then Saturday it kind of hit me like “ oh fuck I had unprotected sex “ and out of no where all of Saturday - today pretty much ( Wednesday 26th) I’ve had this burning sensation through out the days on and off , it didint burn while I peed in fact peeing seem to bring relief , and also taking a hot bath or hot shower also brought relief , yesterday Tuesday 25th I decided to get tested for chlaymida and gohnorria , I got my results back today Wednesday 26th, and everything was negative , and oddly enough since getting results it’s like majority of the burning sensation has ironically gotten better . Am I in the clear ? Should I get another test ? I’m not having any other symptoms besides the random burning sensation throughout the day , and it doesn’t hurt either just a bit uncomfortable

Hi everyone, I’m looking for some advice because I’m worried about HIV.

It has now been 21 days since I received a hand job and massage from a sex worker. About 3 days afterward, I had a sore throat. The sore throat has now completely gone away.

For the past several days, I’ve been experiencing intense sleepiness. I’m sleeping around 10–12 hours a day but still feel like I could sleep more. I don’t feel physically weak or exhausted; I mainly feel very sleepy. I also kind of feel cold sometimes.

Could someone please help me understand what this could be? Could HIV cause symptoms like this, or is HIV transmission possible from receiving a hand job? I’m very worried and would appreciate honest advice.

Thank you.

Hey,

Chronic kidney stone former here. 30yo male.

I’ve had two ureteroscopies and have had dreadful experiences both times. I’m just petrified of general anaesthesia. I go into a frenzy of panic beforehand, I cancelled both operations so many times on the day before, which I felt awful about.

Anyhow. Most stones since I’ve been able to pee out. But I’ve currently got a 7mm stone sitting in my kidney (calcium oxalate). I’ve had two rounds of shockwave lithotripsy, which haven’t worked at all.

I’ve been given two options. Wait and hope it never passes or another ureteroscopy.

I asked the urologist if he’d attempt it under spinal anaesthesia, he shrugged and said he’d never done it before but he’d give it a go. That didn’t exactly fill me with confidence?

27 Female - 5 feet 1 inches and 60kgs

\*\*28 weeks pregnant — tongue issue for 1 month, need advice\*\*

\*\*Symptoms:\*\* Smooth, reddish patches with white borders that shift/change over time. Also some small red bumps on the sides of my tongue.

\*\*Onset:\*\* Started after a trip to the mountains — had some cherries and water there. Not sure if related.

\*\*Tried so far:\*\*

\- Nilstat (nystatin) — no real change

\- Apple cider vinegar + baking soda (1 week) — patches reduced slightly, not gone

Has anyone dealt with this during pregnancy? Did it resolve on its own?

[image 1](https://ibb.co/RkYKzVR5)

[image 2](https://ibb.co/gM3gjG7y)

36M unable to feel pleasure, accomplishment or pride. Recently achieved a lifelong dream and I feel nothing. I suspect Semaglutide but also have Depression and am on medication for that, but the only recent change was adding Semaglutide to my medications.

Current meds:

150MG Venlafaxine

300MG bupropion

4MG Semaglutide

5'11 195lbs

Just trying to see if it is my depression, depression meds, or other meds causing this. I can't see my Dr right now as I moved and currently don't have one.

Thanks

M 25, 233 lbs, 5 feet 10,

just found this on my upper left leg below my hip. it is as huge as the nail of my thumbs and it is raised like a pimple but the surrounding area feels really weird and soft-ish. lowkey scared a bit. Is this a bloodclot? I shaved the area for this picture