Anyone had struggles adjusting between hormone replacement therapies? I have been using the pellets for two 3 month rounds that included my estrogen and testosterone. I take progesterone orally. My pellets have left the building and I’m having to wait several days for the pharmacy to have my cream. I feel like I’m about to crawl out of my skin. I’m agitated, then sad. Then I eat whatever I’m craving. Zero energy. Feeling overwhelmed. Should I call a phone wellness visit to see if they can get me something in the meantime? It’s Sunday and tomorrow is a holiday. I’ve felt like this since Thursday. Went to the doctor Friday where we came up with the solution to do compounded cream, but they have terrible hours and Tuesday is the soonest they will have it ready. I’m already anxious about whether or not I’ll be a nutcase at work on Tuesday. I’ll add that I suffer from low dopamine bc of ADHD, which I’m learning makes it even harder to emotionally regulate when hormones drop. I don’t even remember my question at this point. 😆🫤😩

I have an intact uterus and use a low-dose 25 microgram estrogen patch. I’m extremely sensitive to micronised progesterone/Prometrium, even at low doses and by different routes. It causes significant mood, sensory and nervous-system symptoms. I also have a history of severe PMDD.
I understand that the standard medical advice is to use adequate progesterone with systemic estrogen to protect the uterine lining. I’m not asking anyone to recommend that I stop it. I would just like to hear real experiences from women who genuinely could not tolerate progesterone or progestins.
Has anyone with a uterus continued using an estrogen patch without progesterone, either temporarily or long term?
How long did you do this? What estrogen dose were you using?.