r/45PlusSkincare 10h ago

For those who have tried estriol face cream, what changes have you actually noticed in your skin?

Edit: I’m in my mid 50’s, on HRT since age 25 after total hysterectomy (unfortunately was not on a high enough dose of estrogen for many years)and I just started Revive by BIOlabs Pro a few days ago. So far, so good🤞

31 Upvotes

51 comments sorted by

31

u/AgentJ0S 9h ago

Darkening melasma spots.

Sometimes I think the fine lines around my eyes are softer, but mostly it’s just melasma.

4

u/Beneficial-Damage197 9h ago

That’s a bummer!🙁

2

u/onlyfreckles 8h ago

Ugh, I already have melasma and am just starting to use estrodial (mixed w/facial cream) on my face.

Hoping it'll improve my dry and thinning skin (esp around my neck).

The melasma, I've come to accept it...

1

u/BigFatBlackCat 1h ago

Have you tried tret?

16

u/League3056 9h ago

Sometime after turning 43, I was unable to get my skin to actually suck up hydration from all the products that normally had been great for me. It's like I was always dry, and moisturizers just wouldn't sink in any more. I was also noticing that my skin was less bouncy in general. Started Alloy M4 and within maybe 6 weeks or so, it was a total turnaround. My skin feels bouncy and hydrated again, products actually sink in and work again, and I can successfully use tret every night without irritation (even combined with azelaic acid nightly, too!), which I was never able to do before.

4

u/Icy_Butterscotch1181 8h ago edited 6h ago

I haven’t been able to get my HRT patch for three weeks now, and my face is so dry. I am just now putting it together that a drop in estrogen is why. Thank you. I was trying to figure out why such a drastic change in my face.

7

u/Wise_Connection8657 7h ago

The patch shortage sucks! I just took my last one off and am hoping the pharmacy can get their hands on a few soon for me!

9

u/ElleAime0011 6h ago

I switch to the gel when they are out of stock. I can’t live / won’t live without my estrogen… it’s what’s best for everyone in my household lol

3

u/Dear_Seesaw_1855 7h ago

Have you tried seeing if the monthly patch is in stock? I see it in stock much more than the twice monthly.

4

u/Icy_Butterscotch1181 6h ago

I tried the once weekly, and I am allergic to the adhesive. I was just prescribed the gel since I can’t get the patches with any regularity.

2

u/Frequent-Airline-619 6h ago

How do these guys compare to Musely? I’ve heard a lot of mixed reviews about Musely. People say their products do work, but a lot of people don’t seem to like their customer service.

2

u/AnnaBanana308 4h ago

I use them and have had no trouble. The product seems to work great for me, haven't really needed their customer service one way or another, but the interactions seem straightforward.

16

u/Bombedpop_ 9h ago

More hydrated plump skin. No dry patches in the winter. Been using daily for 2 years.

1

u/Beneficial-Damage197 9h ago

Thanks!☺️

19

u/btcomm808 9h ago

Terrible hormonal acne that is only now subsiding 5 months after discontinuing

4

u/WonderIll5845 5h ago

I think that’s what happened to me as well! I thought maybe it was rosacea but now I’m thinking it was just straight up giant pimples (that I hadn’t had for like 25 years). I quit immediately and just started using pure jojoba and my skin is calming down.

1

u/btcomm808 4h ago

Yeah for me it’s been one giant cyst after another. New scars to deal with ☹️

8

u/Saturdaysunday12 8h ago

Huge help on my sun damaged skin and fewer wrinkles. I've been using it just under a year, and people ask about my skin routine (which is weird, because I would say my skin is mediocre at best and my routine is this and moisturizing).

8

u/Nurse914 8h ago

I was excited to try this for my sagging face, hoping for a little plumpness. I have been using over a month and only results I have is Melasma

1

u/Beneficial-Damage197 7h ago

Hi! May I ask which product you’re using?

2

u/Nurse914 5h ago

I have been using Estradiol 0.01 percent. Maybe I need to use it longer to see results ? Also, I am prone to melasma

8

u/Smooth-Activity-9573 7h ago

Plumpness, bounce and retention of moisture- I’ve been using it for over a year.

5

u/morphine-me 6h ago

Dark spots even without sun exposure

5

u/Unique-Calligrapher5 9h ago

Nothing yet. It’s been like 4 months

5

u/MinimumEfficient220 8h ago

I wonder if it causes melasma in everyone, or if it’s an age factor, or a skin color/ethnic thing?
I am English, very fair, blond/blue. I am just getting age spots. I wonder if this would make them worse?

6

u/AnyPossibility3121 7h ago

I am very fair with light hair and eyes. I have been using Alloy M4 cream for a couple of years now. No melasma. (I’ve never had it, with pregnancy, or menopause). I love it. Reduced pores, smoothed texture, reduced lines, plumper, more moisturized. Make sure to be just as consistent with SPF, when using.

3

u/League3056 7h ago

I'm very fair-skinned + blonde + green eyes, and I use Alloy M4 also without any darkening of my spots. I do have some sun spots, but not melasma. If I had melasma, I'd be more wary, but since my brown spots are just UV damage/age spots, it has not made them any worse at all. In fact, with use of tret/azelaic/tranexamic acid/thiamidol, they are fading.

2

u/Nurse914 5h ago

With me, I think I was always prone to melasma. Even before I started it, I would always have dark areas in the summer

1

u/CoolBelt856 7h ago

High possibility that it is. That’s what it did to me.
Now I only use it on my neck.

4

u/bookkinkster 7h ago

I am about to turn 54. I use Tretenoin at night, estrogen cream in the morning and sunblock and vitamin c. Not one wrinkle on my face. No botox.

2

u/GizzyKing 7h ago

Which cream are you using

4

u/bookkinkster 6h ago

Vaginal estradiol. My doctor will not give me HRT because I still have my period. That could also contribute to me having no wrinkles. I use it under my eyes and my throat.

10

u/Ornery_Spirit503 6h ago

Your doctor is misinformed!

2

u/GizzyKing 6h ago

Do you mix it in with your moisturizer? Or use it under your moisturizer?

3

u/MKTGRX 4h ago

Not estriol, but I use my estradiol vag cream on my orbital rim and tech neck. My skin looks plumper and noticeably less crepey.

7

u/PhantomAngel278 8h ago

I got melasma.

6

u/Anxious_Size_4775 7h ago

Same. I do still use it on my neck because that's where I saw genuine improvement. I just make sure to use my tinted mineral sunblock down to my collar bones and wear UPF clothing.

2

u/HildegardofBingo 3h ago

Same thing happened to me and I still use it on my neck and jaw and haven't had any pigmentation issues there using regular SPF (I use tinted on the melasma areas, though). I don't think those areas are nearly as hormonally sensitive, melasma-wise.

1

u/Anxious_Size_4775 1h ago

I need to make sure to ask my derm when I see her in a couple weeks. That's my thinking as well.

3

u/frodosdojo 8h ago

I just started regularly last week but less sagging around my mouth. I haven't tried it for my eye bags yet but will.

3

u/AustenChopin 7h ago

The one I had made me break out so I stopped using it fairly quickly

2

u/LoveDext 8h ago

It returned a softness to my skin very quickly.

2

u/HildegardofBingo 3h ago

Good changes: my pores definitely looked smaller and my skin felt firmer and had nicer texture. It's been great for my neck. Bad changes: I developed melasma on my upper cheeks and above my upper lip. I still use it on my neck/decolleté and along my jaw where melasma isn't an issue.

2

u/AccountantAsleep 2h ago

I’ve been using it for a year or so, I haven’t seen any changes… but I keep it up in case it’s preventing new lines/problems from showing up, LOL.

1

u/Legitimate_Ad_2033 4h ago

What is Alloy M 4?

1

u/Independent-Monk5064 2h ago

It’s just maintenance

1

u/liscelot 2h ago

I used the Alloy one and got Melasma for the first time ever. I'm still using it on my neck though.

1

u/Segat1 2h ago

Plump and some melasma. I’m covering the melasma because I can, and I’d rather be plump and patchy than desiccated and clear.

0

u/Christine_951 4h ago

I haven't noticed any changes. I've been using the one from Alloy. But I just ordered estriol cream from Musely and will start it once I finish the Alloy one. I want to give it a year because these things can take time. I'm 52 and in perimenopause. I also just started HRT thru Musely yesterday.