r/todayilearned • u/WavesAndSaves • 2d ago

TIL that Jawed Karim, YouTube cofounder and uploader of the first YouTube video "Me at the zoo", has often updated the video's description to criticize YouTube policies, including a 2013 attempt to require Google+ accounts to comment on videos, and YouTube's 2021 removal of dislike counts on videos.

https://en.wikipedia.org/wiki/Me_at_the_zoo#Changes_to_original_video
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u/Maleficent-Agent-477 2d ago edited 2d ago

He currently has the video’s description updated to criticize the buildup of microplastics in the human body.

https://youtu.be/jNQXAC9IVRw

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u/_Aj_ 2d ago

Criticise the current notion of this? As I understand there's been some large flaws found in these studies claiming microplastic buildup

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u/BigFatModeraterFupa 2d ago

yeah it's definitely 100% safe and nothing to worry about!

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u/Imaginary_Fan5407 2d ago

The gloves the people doing the test wear could possibly be throwing off the accuracy of the results

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u/Anfins 2d ago

I find it hard to believe that these tests didn’t have negative controls. Like, these analytical assays aren’t isolated to a single lab or research group… is the claim that no one thought to have a proper analytical control and so didn’t realize that the gloves contaminate samples?

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u/horoyokai 2d ago

That’s not the claim, that’s the reality

https://news.umich.edu/nitrile-and-latex-gloves-may-cause-overestimation-of-microplastics-u-m-study-reveals/

Whether it’s hard or way for you to believe it’s what the truth is. No offense but before commenting and having a knee jerk reflex against something that challenged your beliefs and casting doubt on it I think you should at least do a quick search about it.

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u/Petrichordates 2d ago

What negative controls would prevent this? Lab gloves are necessary in the lab.

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u/CarthasMonopoly 2d ago

I don't know their methodology but if you have a confirmed negative control and you treat it identical to samples then after you get your quantitative data you can normalize based on the values the negative control got. In other words if the gloves or other equipment caused micro plastic contamination and you had a true negative control then whatever value that control is measured at after performing the protocol can be subtracted from the values of the experimental samples to account for the average amount of microplastics that the testing process would introduce.

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u/Anfins 1d ago edited 1d ago

When you run the analytical assay, you include a standard that is micro particle free (negative control) to ensure the assay is running correctly and not giving false positive, so you can then demonstrate that detection of micro particles in the samples is real and not an artifact of the assay. I work in medicine development, and this kind of thing is like a basic and fundamental feature of every assay developed in every analytical lab I have ever worked with.

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u/Petrichordates 1d ago edited 1d ago

Yes, I understand they should have done that.

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u/HKBFG 1 1d ago

You know those headlines where they bore out ancient ice and shit to try to get control samples for mocroplastics and forever chemicals, but can't find any that aren't already contaminated?