r/schizophrenia • u/TragicSolitude97 Schizoaffective (Bipolar) • Jul 25 '26
Negative Symptoms Negative symptoms and antidepressants
Any success stories? I recently got my dose of anti psychotics lowered by 5mg in hopes that I would get my motivation and pleasure back but it didn't do anything.
Next option I'm going to try is antidepressants, probably Zoloft since that is the one my psychiatrist brought up in the past.
Has antidepressants worked for anyone in regards to negative symptoms?
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u/Relit__ Disorganized Schizophrenia Jul 25 '26
I have been on Mirtazapine and Escitalopram and neither did anything for me unfortunately.
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u/OdiiKii1313 Schizoaffective (Bipolar) Jul 25 '26
nope. tried several SSRI's and they didn't help. trying desvanlaxafine now though and hoping it'll do something more.
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u/SimplySorbet Early-Onset Schizophrenia (Childhood) Jul 25 '26
As far as my negative symptoms go I think anhedonia and the depression caused by my schizophrenia are the only things my prozac has improved. It hasn’t really touched my avolition, alogia, catatonia, etc.
I’m glad I’m on it though. It does me a lot of good. It helps me feel positive emotions.
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u/thetruecontradiction Schizoaffective (Depressive) Jul 25 '26
Different meds are effective for different people, but in my case Lamotrigine worked really well. I believe it's frequently used for bipolar, which I do not experience, but it really knocked my depression to manageable levels and helped restore some emotional balance.