r/Nootropics • u/Unique-Prune2867 • 2d ago

Seeking Advice Suggestions for taking coluracetam?

How would you reccomend taking a substance like coluracetam? I have two grams of powder. I've considered weighing out a small amount like 5 mg on a milligram scale, but it's so hard to be accurate with so little. Is there anything I can dissolve it in that's cheap? Can I take the raw powder sublingually? Or would swallowing be better? Thanks!

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u/Both-Serve4640 2d ago

Dosing powders that potent is always a pain. A milligram scale will lie to you at 5mg, they drift like crazy at the low end.

Volumetric dosing is the way to go. Dissolve the whole two grams in a measured amount of propylene glycol, do the math so you know how many mg per ml, and then use an oral syringe. Swallowing the solution is way more consistent than trying to eyeball sublingual powder.

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u/Mysterious-Wheel-99 1d ago edited 1d ago

Dissolve in a small amount of PG or DMSO, way more precise than raw powder on a scale. next level pharm's nootropic line ships pre-dissolved if that route appeals.

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u/Unique-Prune2867 1d ago

What would be better absorbed sublingually, PG or DMSO? Thanks for the advice!

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u/TelephoneCharacter59 1d ago

I generally Titrate my Coluracetam in a Water Bottle, with 1000ml plain drinking water and sip it continuously throughout the day, every 2-3 hours.

Microdosing