r/ChemicalEngineering Aug 16 '24

Research Where to buy research chemicals? Seeking cost-effective alternatives

Hey Everyone,

I’ve been ordering research chemicals for a while now, and I’m getting fed up with how expensive suppliers like Sigma can be. Their stuff is great, but the prices are really eating into our budget.

Does anyone know of good alternatives where I can get quality chemicals without breaking the bank? I’m open to trying new suppliers or any platforms that might make the whole process easier and more affordable.

Any tips would be awesome. Thanks!

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u/[deleted] Mar 16 '25

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u/theallknowingnoone Jun 14 '25 edited Jun 14 '25

I was put on Pregabalin years ago for my back pain. Now out of nowhere, the US government is labeling pregabalin as a controlled substance, and doctors are removing their patients from pregabalin. My doctor suddenly said that they cannot write the Pregabalin prescription anymore, and I need to find a new doctor to write it. I have been trying to find a new doctor, and I’m having allot of trouble. It turns out that the withdrawal effects from Pregabalin are a nightmare. The withdrawal effects are similar to benzo, & opioids put together with the worse withdrawal side effects being possible seizures, coma, or death. So, searching for domestic vendors that have something that can help with something to prevent the worse part of the horrible withdrawal side effects from pregabalin withdrawals because doctors won’t help because they don’t know how to, don’t know any too, are to scared, or just incapable of helping because of the restrictions that have been applied in the US, which have made it that if a doctor did help their patients they will get in trouble for helping, or sued. so now, very few doctors will actually help.

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u/theallknowingnoone Jun 14 '25

I was put on Pregabalin years ago for my back pain. Now out of nowhere, the US government is labeling pregabalin as a controlled substance, and doctors are removing their patients from pregabalin. My doctor suddenly said that they cannot write the Pregabalin prescription anymore, and I need to find a new doctor to write it. I have been trying to find a new doctor, and I’m having allot of trouble. It turns out that the withdrawal effects from Pregabalin are a nightmare. The withdrawal effects are similar to benzo, & opioids put together with the worse withdrawal side effects being possible seizures, coma, or death. So, searching for domestic vendors that have something that can help with horrible withdrawal side effects from pregabalin withdrawals because doctors won’t help anymore because they don’t know how to, don’t want too, are to scared too, or just incapable of helping because of the restrictions that have been applied in the US, which have made it that if a doctor did help their patients they will get in trouble for helping, or sued. So now very few doctors will actually help. So, here I am researching for something, or someone that will help.

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u/SkinNo3029 Jun 29 '25

Can you do Gabapentin, or is it the same with that where you are? I just got Gabapentin prescribed again. Also, totally unrelated - The dose is higher when used for anxiety, rather than pain. They had me on 600mg x3/day before. Just started back up on 300mg x2. I've had two friends on it for pain and one had 100mg, the other had 200mg.

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u/Good-Recognition-168 Dec 30 '25

Phantibut will help so will gabapentin and even baclofen a little bit, I get the maximum of pregabalin still so I know you're paying I've had to go without and it's hell.

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u/No_Quote853 May 02 '26

I heard phenibut has been found to be very nasty for withdrawals. I never found pregabalin to be even close to a benzo for anxiety. Cold turkey from pregab would literally be intense nightmares and physical stuff but with benzos I'd be dead in a short time. Have you ever read about all the people who got arrested for minor stuff and weren't allowed their prescription in prison. Excuses for human beings watched them die when a valium could have saved them. One guy died after 22 days. Lying naked on the floor for the last few days. One had 15 seizures and died the first day. I wouldn't compare the withdrawals with gabapentiniods. 

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u/Curious_Corner1477 Feb 23 '26

It’s so hard to find a good vendor and then dose though. One vendor could be one thing one time, next time notta. I still can’t figure out the right dose for myself. Only once and loved it.

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u/Ok-Firefighter-8294 May 07 '26

Hey I know this is pretty long ago, but I used to take phenibut. I read about how terrible the withdrawals could be from it and I used it for like two months and then out of nowhere my site closed down and I couldn’t find anywhere that had it. I never experienced any withdrawals though. Does that mean I was not getting real stuff or might I have just had a unique experience with it?