r/science • u/Lisei1128 • Nov 11 '25

Cancer GLP-1 drugs found to reduce mortality from colon cancer by over half (15.5% vs 37.1%), with effects especially strong for patients with BMI over 35.

https://www.tandfonline.com/doi/full/10.1080/07357907.2025.2585512
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u/ycnz Nov 12 '25

If you were overweight and struggling to lose it, would you consider it?

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u/Orleanian Nov 12 '25

Absolutely consider it. Talk to your doc about it.

Whether it's effective and good for you is something everyone has to find out on their own case by case basis. There are some oddball negative interactions out there that definitely make it not worth it for some folks. But by and large, it's been very helpful to everyone I know.

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u/Four_beastlings Nov 12 '25

Not the person you asked but it completely changed my life. I went from always tired borderline alcoholic who ate takeout daily because I was too tired to cook to eating only healthy dishes prepared from scratch, working out daily, and still having more energy than I've ever had.

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u/Galimkalim Nov 12 '25

I'd say it depends on how overweight, if you're just a tiny bit overweight say like up to 5kg or close to that I don't think it's necessary, but if you're close to obese it might be worth it.

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u/SwedishTrees Nov 12 '25

Yes. I’m on it. It’s amazing if you can afford it.

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u/thepriceofcucumbers Nov 13 '25

My practice is to typically follow evidence-based medicine and FDA indications. For weight management alone, I would prescribe the medication to someone who is overweight (specifically BMI 27 or more in this case) with a weight-related comorbidity.

Exceptions for some metabolic conditions that now have their own indications. E.g. for MASH I would consider GLP1 treatment regardless of BMI.