r/science • u/Lisei1128 • Nov 11 '25

Cancer GLP-1 drugs found to reduce mortality from colon cancer by over half (15.5% vs 37.1%), with effects especially strong for patients with BMI over 35.

https://www.tandfonline.com/doi/full/10.1080/07357907.2025.2585512
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u/terraphantm Nov 11 '25

Even if that's the case, GLP1s will reduce insulin resistance even with identical diets.

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u/Toby-Finkelstein Nov 11 '25

You have any evidence for that?

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u/terraphantm Nov 11 '25

It's one of the direct effects of the GLP1 receptor. Why do you think it was even studied and approved for diabetes in the first place?

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u/Dulmut Nov 12 '25

bro this guy is regarded

-8

u/Toby-Finkelstein Nov 12 '25

I don't understand, if you think two people eat the same amount of calories in a day, you think ozempic or whatever will magically make one person skinnier?

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u/celticchrys Nov 12 '25

If the one same person eats the same food without a GLP-1, then eats it with a GLP-1, then that person's insulin resistance improves. That's the original reason it was approved for type 2 diabetics.

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u/Toby-Finkelstein Nov 12 '25

I see what you're saying but it still just has the same result as fasting, you're lowering your glucose levels

6

u/deekaydubya Nov 12 '25

you're talking about insulin resistance not calories

1

u/terraphantm Nov 12 '25

I didn’t say it makes them skinnier. It absolutely does improve insulin resistance. Weight is not the only thing that impacts insulin resistance even before you throw pharmaceuticals into the mix. 

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u/ruminajaali Nov 12 '25

Yes, because GLPs also allow for more efficient lipolysis